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Mental & physical health

Get emergency treatment (PEP) after recent exposure to HIV

PEP (post-exposure prophylaxis) is a medicine that can be taken for 28 days to prevent HIV infection after you have been exposed. PEP must be taken within 72 hours, or 3 days, from the time of exposure.

Call (833) 933-2815 any time to be connected to Philly’s 24/7 PEP hotline.


PEP is a medicine used to prevent HIV infection after a possible exposure. Sources of exposure to HIV include:

  • Condomless sex or having a condom break during sex with a partner who is living with HIV, or with a partner whose HIV status is unknown.
  • Sharing equipment for injection drug use (such as needles, syringes, and cookers).
  • Sharing needles or syringes for hormone therapy.
  • Sexual assault.

Where and when

You can get PEP from your doctor or local emergency department. If you do not have a doctor or your doctor doesn’t know about PEP, you can go to Health Center 1 (1930 S. Broad St., 2nd floor) and say that you may have been exposed to HIV. A healthcare provider will ask you some questions to determine if you are a good candidate for PEP. Treatment and follow-up are available onsite for those with a possible exposure occurring within the recommended 72-hour time frame.


The cost of PEP varies depending on where you get it and may be free depending on your insurance. We are here to help, regardless of ability to pay or immigration status. Call the Health Information Helpline at (215) 985-2437 to find out where you can get PEP.